Signalling Nanodomains Lab Visualising the structures of intracellular communication, one molecule at a time

I completed my university studies (BSc. 1st class Hons with a major in Cardiovascular Biology and PhD in Physiology) in the University of Auckland (NZ), with one of the earliest studies on using super-resolution to study ryanodine receptors in the heart. My postdoctoral trainings were in the Department of Physiology of the University of Auckland (2010-2011), School of Biomedical Sciences of the University of Queensland (2011-2013) and the College of Physics of the University of Exeter (UK; 2013-2015). I founded my first independent research group in the University of Leeds (UK) in 2015 which led to a number of innovations in super-resolution microscopy methods including an enhanced version of Expansion Microscopy and a fast localisation microscopy method called sandSTORM. In 2019, I was awarded a 7-year UKRI Future Leader Fellowships, which launched my Sheffield-based group and a vision of making super-resolution and high-resolution microscopies more accessible to the broadest range of Life Scientists. In 2023, I moved to UNSW to take up the role of Head of Department of Molecular Medicine. Here, I started the new base for the Signalling Nanodomains Lab to build the newest phase of research into cardiac ryanodine receptors and their structural and functional organisation. Adjacent to my scientific research, I work on advancing the equity, diversity, and inclusion (ED&I) in STEM. I write papers, advocate for marginalised people in science and advise on building inclusive research cultures in universities and funding organisations. Outside of my academic roles, I am interested in social and political issues, running, tech and Latin dance.

Search for Dr Izzy Jayasinghe (she/her)'s papers on the Research page